INTERFERENCES OF HEPATITIS VIRUS C INFECTION IN GINGIVO-PERIODONTAL PATHOLOGY
Ioana Rudnic, Dorina-Cerasella Sincar, Liliana Pasarin, Stefan Lucian Burlea, Erica Rudnic, Ioana Andreea Sioustis, Bogdan Constantin Vasiliu, Sorina Mihaela Solomon
Hepatitis C virus infection may involve a variety of extrahepatic disorders, including the oral cavity, with some oral manifestations being oral diseases such as lichen planus and sialogensis similar to sjogrene sindrome. Sometimes, patients may have two possible patterns of hepatitis virus infections, either coinfection, when viruses infect the patient at the same time, or superinfection, when the infected patient is later exposed to a second type of hepatitis virus, such as HBC and HDV and HBV or HCV. Purpose of the study: In order to verify the hypothesis that chronic hepatitis C may be an unfavorable factor for the development of periodontal disease, we have developed a study to make associations between periodontal and hepatic pathology at the clinical level. Material and method: The test or study group consisted of 43 patients who were divided into two subgroups, 23 hepatitis B positive patients representing the first subgroup and 20 hepatitis B and C positive patients, the second subgroup. The control group consisted of 20 adults of the same age and healthy individuals with no history of systemic disease. Results: There were a significant differences in comparison of hepatitis B group with the subgroups of hepatitis B and C. This is due to the fact that liver dysfunction can be presented through many oral manifestations such as mucosal jaundice, bleeding disorders, staining, bruising, gingivitis, bleeding, xerostomia and oral pain. Conclusions: Known clinical observations and sporadic investigations of the oral mucosa highlight the interplay of liver function with trophic and integrity of the oral and digestive mucosa in general.