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Romanian Journal of Medical and Dental Education Volum 8 Issue 4, 2019 PARTICULARITIES OF PHARMACOVIGILENCE ACTIVITY IN DENTISTRY

PARTICULARITIES OF PHARMACOVIGILENCE ACTIVITY IN DENTISTRY

Ioana Maria Hunea, Cristina Mihaela Ghiciuc, Irina Grădinaru, Daniela Anistoroaei, Georgeta Zegan

ABSTRACT

The success of pharmacovigilance is based on the adverse drug reaction (ADR) reports, this contributing to the identification of problematic drugs or dental materials. Our paper aim was to identify the factors influencing to the pharmacovigilance regarding knowledge, attitude, and behaviour among dental practitioners. Material and methods. Articles were selected from MEDLINE/PubMed and Web of Science all databases. Case reports, case series, reviews, abstracts to the meetings, studies presenting only data about the efficacy of the treatments and duplicate studies were excluded. We recorded the characteristics of the study, the evaluated parameters and the factors contributing to the attitude to report the adverse effects. Results. From the 82 papers retrieved, there were selected 7 papers. These were cross-sectional studies using self-administered questionnaires had a wide response rate (from 25% to 100%) and included groups from dental students to first year dentists or dental practitioners. Incomplete knowledge about ADR and lack of training of ADR reporting manifested through the difficulties in deciding the occurrence or not of an ADR and through concerns that the report may be wrong are the main factors contributing to the low reporting rate among dentists. Conclusions. Early recognition of an ADR, followed by its report to a pharmacovigilance centre contributes to the identification of problematic drugs or dental materials.

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