Forna Norina, Costuleanu Marcel, Chetrus Viorica, Agop-Forna Doriana, Sălceanu Mihaela, Topoliceanu Claudiu, Cârlan Delia, Morhan Sebastian, Zelinschi Dragoş, Lazaruc Dana
Aim of study. The assessment of the postoperatory healing processes in guided tissues regeneration by association of plasma rich in growth factors (PRGF) with xenograft. Materials and method. The study group included 24 edentulous patients, candidates to dental implants (age 30-65); the patients were planned for pro-implant procedures by alveolar augmentation and guided tissues regeneration techniques with delayed implantation (6-8 months). The patients were selected from Clinical Base of Dental Education, Faculty of Dental Medicine, U.M.F. ˝Gr.T.Popa˝ Iasi and 2 private dental practices. The informed consent was obtained. The patients required guided bone regeneration technique to improve alveolar bone parameters in implant sites areas with moderate and severe defects. A combination of xenograft (Hypro-Oss, BioImplon) and Plasma Rich in Growth Factors (PRGF, Endoret) was used as grafting material. The postoperatory healing processes were monitorised by recording of the rate of complications and success rate. Results. The association of plasma rich in growth factors (PRGF) with xenografts materials is associated with postoperatory complications in only 6-12% cases and has 94% success rate în pro-implant alveolar augmentation. Conclusion.PRGF technology can be used for new combinations with potential to increase the clinical effectiveness of the guided tissues regeneration techniques in oral surgery.