Raluca-Cristina Mocanu, Marius Maris, Irina-Georgeta Sufaru, Ionut Luchian, Diana-Maria Anton, Georgeta-Maria Laza, George-Alexandru Maftei, Mihaela Maris, Maria-Alexandra Martu
The antimicrobial potential of photodynamic therapy has been known since the beginning of the last century. Photodynamic therapy products cause damage to various components of microbial cells or can irreversibly alter metabolic activity. This leads to microbial elimination. This mechanism of action is based on the energy absorbed by intracellular photosensitization which is transferred to the oxygen molecule to damage the oxidative reaction pathways in the plasma membrane and the genetic material of microbial cells. This effect is limited to microbial cells with no toxic effects on host cells. Based on the advantages and characteristics of antimicrobial photodynamic therapy, it has been proposed that periodontal and peri-implant diseases be potential targets of this new type of chemotherapy.