Ada Stefanescu, Irina-Georgeta Sufaru, Maria-Alexandra Martu, Victor Costan, Kamel Earar
Abstract
Periodontology has adapted over the years to demands for better healing, a more comfortable solution, treatment of marginal tissue recessions, and better aesthetics. This has become one of the main goals of this discipline. Platelet-enriched fibrin (PRF) is an autologous platelet concentrate similar to a scar matrix that guides the various cellular elements and releases growth factors and cytokines near the injury. It is an autogenous alternative to conjunctive grafting in treating gingival recession that would allow optimal healing quickly. This review presents the different types of PRF, the protocols for obtaining them, and the practical features of their surgical applications. The use of PRF in oral surgery signifies not just a trend but a fundamental shift towards patient-centered, evidence-based, and minimally invasive practices that redefine the boundaries of what is achievable in modern oral healthcare.