Irina-Georgeta Sufaru, Maria-Alexandra Martu, Liliana Pasarin, Ionut Luchian, Diana Tatarciuc, Sorina-Mihaela Solomon
Abstract
The interplay between oral health and systemic conditions continues to unfold, with an emerging focus on the association between periodontal disease and chronic kidney disease (CKD). Periodontal disease, a chronic inflammatory condition affecting the supporting structures of the teeth, has garnered attention beyond its oral implications. Recent research suggests a bidirectional link between periodontal health and CKD, with inflammatory mediators and immune responses serving as potential conduits for mutual influence.
The review navigates through the current understanding of how periodontal disease may contribute to the progression of CKD and vice versa. Inflammatory pathways, oxidative stress, and microbial translocation are among the key elements linking these seemingly distinct entities. Recognizing periodontal disease as a potential modifiable risk factor in CKD emphasizes the importance of comprehensive oral health assessments in renal care.
Furthermore, understanding the shared inflammatory cascades opens avenues for integrated preventive strategies that span both dental and nephrological disciplines. As research in this field advances, a holistic approach to patient care that considers both periodontal and renal health becomes paramount for effective prevention and management strategies.