Irina Grădinaru, Loredana Liliana Hurjui, Mădălina Andreea Donos, Violina Budu, Adina Oana Armencia, Carina Balcoș, Daniel Paval, Jehac Alina Elena, Magda-Ecaterina Antohe
Thus, gingival hypergrowth should be considered as a particular form of gingival diseases. As mentioned in the presentation of gingival and periodontal diseases, hypergrowth can be determined by a large number of factors, the most common of which is poor oral hygiene, which through chronic inflammation increases the volume of gingival tissues, increases the bleeding tendency, the surface of the gingival mucosa lose the lobulated appearance. In the case of medicinal gingival hypergrowth, along with the inducing factor represented by the drug (nifedipine, phenytoin and ciclosporin A), poor oral hygiene has a primary role in its occurrence and development . The relationship between the extent and severity of gingival overgrowth and a variety of drug variables (dose, duration, serum and saliva concentration) is a controversial issue. Many researchers agree that there is a certain concentration of the drug in the blood, basic or threshold, which when exceeded can lead to the appearance of gingival hypergrowth and this concentration is variable from individual to individual .