Cepoi Irina Gabriela, Agop-Forna Doriana, Clipa Larisa
ABSTRACT
Full-arch rehabilitation of edentulous patients remains one of the major challenges in contemporary prosthodontics. Over the last two decades, the All-on-4 concept has emerged as a predictable alternative to conventional removable prostheses and extensive implant-supported rehabilitation protocols requiring multiple implants or bone grafting procedures. The concept relies on four strategically placed implants, including two axially positioned anterior implants and two tilted posterior implants, allowing increased anteroposterior spread and reduction of distal cantilevers.
The purpose of this narrative review is to analyze and synthesize recent evidence regarding the principles involved in the fabrication of implant-supported full-arch prostheses within the All-on-4 concept. Seven recent publications addressing biomechanical considerations, prosthetic planning, digital workflows, restorative materials and peri-implant health were reviewed.
Current literature demonstrates that long-term success depends on several key factors, including prosthetically driven implant placement, cantilever control, optimization of anteroposterior spread, passive framework fit, appropriate restorative material selection and maintenance of peri-implant health. The integration of digital technologies and artificial intelligence-based design optimization has further enhanced treatment accuracy and predictability.