Sorina Mihaela Solomon, Alexandra Martu, Ionut Luchian, Irina Georgeta Sufaru, Ioana Sioustis, Liliana Pasarin, Andrei Nicolau, Cristian Martu
Very few studies have attempted to study the relationship between chronic illicit drug abuse and intra-oral pathological events. Despite the well-documented negative effects of illicit drug use, the use of these agents continues to increase. It has long been recognized that a series of drugs can cause certain periodontal tissue changes and influence the clinical onset or progression of periodontal disease. Many studies have reported side effects of illicit drug use on oral and rhinosinusal tissues, but most of them are limited to case reports. It seems that well-controlled and systematic studies are needed, but these are difficult to carry because of the nature of the population studied, as well as its complexity in accessing numbers of subjects large enough to carry out meaningful analyzes.